Be careful on what you wish for… A dream came true for Regine Sta. Maria as she debuts as a news anchor for the evening news. After the newscast, she received a bouquet of flowers and a phone call from someone who calls himself her Number One Fan. His message: make him number one or else, someone will die. The next day, she dismissed it as a mere prank. After a week, the police found her Journalism professor dead. She realized that Number One Fan proved his threat. Journalists start to die one by one and Regine had to guess who Number One Fan is. But how if her only clue was the tune of Twinkle, Twinkle, Little Star?